Nail manifestations in COVID-19: a scope review
DOI:
https://doi.org/10.52076/eacad-v3i3.347Keywords:
COVID-19; Nails; Microcirculation; Inflammation.Abstract
In addition to the classic signs and symptoms, a variety of manifestations in different organ systems have already been reported during SARS-CoV-2 infection. Growing numbers of studies on dermatological manifestations are found in the world scientific literature. In contrast, nail changes are still a gap in knowledge about COVID-19 because they have been recently recognized. Considering the increased awareness of the cutaneous manifestations of this infection, it is vital to investigate the associated nail changes to favor early diagnosis, more precise interventions and better prognosis in patients with COVID-19. The objective is to carry out a scoping review to expand knowledge about the nail changes attributed to COVID-19 and the likely pathophysiological process that determines its development. The present scoping review was conducted according to the extension of the PRISMA-ScR strategy, considering only articles in English published between the years 2020 and 2022 in the PubMed database. The electronic search strategy used was ["nails" AND "COVID-19"]. 52 studies were retrieved and 18 were included to compose the baseline literature for the review. Several nail changes have already been attributed to COVID-19, specifically red lunulas, Beau's lines, leukonychia, onychomadesis, orange transverse lesions, COVID-toes, multiple retronychia, shoreline nails, Lindsay's nails, and Terry's nails. It is evident that more studies need to be carried out to investigate in more detail the nail changes caused by COVID-19 for a better understanding and for their management to be improved.
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Copyright (c) 2022 Anna Francesca Colonello Pennacchi; Sabrina Ferreira Akiyama; Lara de Brito Junqueira; Victoria Carolina Varaldo Prette Queiroz de Sousa; Ana Cláudia Cavalcante Espósito Lemos
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