Analysis of the incidence and predisposing factors for recurrence of Henoch-Schönlein Purpura in pediatric patients

Authors

DOI:

https://doi.org/10.52076/eacad-v3i3.311

Keywords:

IgA Vasculitis; Henoch-Schönlein Purpura; Incidence; Risk factors; Recurrence.

Abstract

Henoch-Schönlein purpura (HSP) is a disease characterized by systemic inflammation of small vessels, mediated by IgA. The classic tetrad is composed of non-thrombocytopenic palpable purpura, arthritis, abdominal pain, and glomerulitis with hematuria. The disease is triggered by numerous viral and bacterial infections and is usually self-limiting. However, there are cases in which HSP affects multiple organs and, through predisposing factors, becomes recurrent and severe. Therefore, the aim of the study is to analyze the incidence and predisposing factors for recurrence of Henoch-Schönlein purpura in pediatric patients. This is an integrative literature review, which used the PubMed (Medline), Scientific Electronic Library On-line (SciELO) and Cochrane Library platforms as databases for the selection of scientific articles, all in English, with a temporal cut of 2017 to 2022. According to the literature analyzed, it is concluded that the average annual incidence of Henoch-Schönlein Purpura in pediatric patients is 9 per 100,000 inhabitants, which varies according to the location. In addition, the main risk factors for the recurrence of the pathology are HSP with renal involvement, patients on corticosteroid therapy, in addition to allergopathies, such as allergic rhinitis and atopic dermatitis.

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Published

28/10/2022

How to Cite

Amate, C. G. de O. ., Cruz, I. C. L. ., Souza, I. M. V. ., Daher, H. C. D. ., Freitas, G. A. ., Silveira , F. C. A. R. da ., Bona, L. M. A. ., Moraes Neta , A. L. ., Leão, M. S. ., Dantas, A. T. de A. ., Silva , S. G. M. ., Cavalcante, L. S. ., Cavalcante, E. B. ., Curry, A. M. ., Reis, C. G. ., Machado Filho, D. E. C. ., Moraes, R. da S. ., Pereira, S. G. P. J. ., Menezes, M. S. ., Albuquerque Rocha Aquino , M., Nunes, I. E. ., Sousa, A. C. C. M. ., Temóteo, G. de A. ., Rodrigues, M. R. G. ., Freitas, G. A. ., Amorim, V. D. ., Cavalcante, L. R. ., & Vidal, A. R. L. . (2022). Analysis of the incidence and predisposing factors for recurrence of Henoch-Schönlein Purpura in pediatric patients. E-Acadêmica, 3(3), e3233311. https://doi.org/10.52076/eacad-v3i3.311

Issue

Vol. 3 No. 3 (2022)

Section

Health and Biological Sciences

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Copyright (c) 2022 Carolina Gomes de Oliveira Amate; Isabela Chaves Lira Cruz; Irlane Moraes Vasconcelos Souza; Heitor Campos Damião Daher; Geovana Alencar Freitas; Felipe Cesar Aquino Ramos da Silveira ; Lina Monteiro Andrade Bona; Antonina Linhares Moraes Neta ; Mariana Santiago Leão; Antonio Tito de Araujo Dantas; Suellen Guimarães Melo Silva ; Lucas Sousa Cavalcante; Emanuela Barros Cavalcante; Alessandra Magalhães Curry; Carlena Góes Reis; David Eulálio Couto Machado Filho; Renata da Silva Moraes; Sâmia Gisely Pinto Jansen Pereira; Marina Santos Menezes; Marcelo Albuquerque Rocha Aquino ; Isabelle Ewerton Nunes; Andressa Cristina Correa Machado Sousa; Guilherme de Alencar Temóteo; Mara Rita Gonçalves Rodrigues; Gabriela Alencar Freitas; Vinicius Duarte Amorim; Lara Raposo Cavalcante; Alexandre Rodrigues Lobo Vidal

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