Pott's Disease associated with paraplegia: A case report of osteoarticular tuberculosis

Authors

DOI:

https://doi.org/10.52076/eacad-v3i3.293

Keywords:

Pott's Disease; Extrapulmonary tuberculosis; Koch's Bacillus; Paraplegia; Spine biopsy.

Abstract

Pott's disease is the term used to define infection of the spine by Mycobacterium tuberculosis. Extrapulmonary involvement occurs through lymphohematogenous dissemination of bacilli. The development of the abscess compresses the spinal cord causing low back pain, paraparesthesias, paraparesis, difficulty in walking. The aim of this study was to describe a case of osteoarticular tuberculosis, addressing its clinical presentation, diagnosis and treatment. B.F.F, female, 43 years old, was admitted to a public referral hospital in São Luís with a clinical picture of unspecified encephalomyelitis, paraplegia, infectious spondylodiscitis with pathological fracture due to collection in the thoracic spine (T5/T6), where it was observed empyema with spinal cord compression (ICD-10: G952) after MRI and CT scan. The patient was confined to bed and had severe functional disability. The clinical picture of the current disease started 3 months ago, with severe chronic neuropathic pain. She was monitored daily by the hospital's physiotherapy team for functional rehabilitation and the nursing team for general care. A posteriori, there was drainage of one of the infectious foci, which was biopsied for histopathological examination, confirming the diagnosis of Pott's disease. He currently uses rifampicin, isoniazid, amitriptyline, baclofen, gabapentin, clonazepam and omeprazole on a daily basis. The patient continues with deep, cutaneous-abdominal areflexia, grade 0 strength and loss of sensation in the lower limbs. Sometimes the diagnosis of Pott's Disease is delayed due to the non-specificity of symptoms confused with lumbosciatic pain. Its real identification occurs when there is already some bone deformity or nerve injury.

References

Al-Mahmood, M. R. (2022). A case report of a young woman with spinal tuberculosis. Hemoglobin (g/dl), 9, 10.

Albanese, G., & Gabriela, J. (2019). POTT'S DISEASE STILL A CHALLENGE NOWADAYS. Acta Medica Marisiensis, 65.

Avcu, G., Bal, Z. S., Duyu, M., Akkus, E., Karapinar, B., & Vardar, F. (2015). Thanks to trauma: a delayed diagnosis of Pott disease. Pediatric emergency care, 31(12), e17-e18.

Brito-Núñez, N. J., Campos, L., Díaz, F., Velasquez, M., Izaguirre, E., Faria-Méndez, G., ... & Krivoy, J. (2019). Tratamiento quirúrgico de la espondilitis tuberculosa (enfermedad de Pott). Reporte de un caso y revisión de la literatura. Revista biomédica, 30(2), 59-65.

Cantwell, L. M., Perkins Jr, J. C., & Keyes, D. C. (2018). Pott's disease in a patient with subtle red flags. The Journal of Emergency Medicine, 54(3), e37-e40.

Chicué, L. V., Bisso, I. C., & Heras, M. L. (2021). Pott disease: Vertebral Tuberculosis. Revista da Sociedade Brasileira de Medicina Tropical, 54.

Cucuzza, M. E., La Mendola, F., D’Ambra, A., Smilari, P., Greco, F., Fiumara, A., & Praticò, A. D. (2018). Pott disease in a 14-year-old girl affected by congenital lamellar ichthyosis type 3 and diabetes mellitus. Journal of global infectious diseases, 10(3), 166.

Hima-Maiga, A., Kpelao, E., Kelani, A. B., Abdoulwahab, I., Diop, A., Sanoussi, S., & Sakho, Y. (2020). Le Mal de Pott Dorsal au Niger: aspects épidémiologiques, cliniques, thérapeutiques et évolutifs. Health Sciences and Disease, 21(10).

Jurca, C. F., Rios, C. A. G., de Lima, L. F. G., de Toledo, R. A., Rodrigues, V. O., & dos Santos, R. O. (2017). MAL DE POTT: UM RELATO DE CASO. Anais da Mostra de Saúde.

Kalamara, E., Ballas, E. T., & Petrova, G. (2020). Pott disease: when lumbar pain is not innocent. Advances in Respiratory Medicine, 88(6), 608-611.

Kotil, K., Alan, M. S., & Bilge, T. (2007). Medical management of Pott disease in the thoracic and lumbar spine: a prospective clinical study. Journal of Neurosurgery: Spine, 6(3), 222-228.

Lima, H. N., Pires, R. B., de Carvalho, A. G., Rythowem, I. V. B. S., Junior, P. M. P., & Silva, C. L. R. (2020). POTT DISEASE IN IMMUNOSUPPRESSED PATIENT, A CASE REPORT. Revista de Patologia do Tocantins, 7(1), 52-54.

Maron, R., Levine, D., Dobbs, T. E., & Geisler, W. M. (2006). Two cases of pott disease associated with bilateral psoas abscesses: case report. Spine, 31(16), E561-E564.

Patel, N., Patel, R., Krysztofiak, M., & Sundaresh, K. V. (2020). A Case of Pott's Disease: Typical Presentation of an Uncommon Disease in the United States.

Quispe, Y. L. F. (2020). La Tuberculosis vertebral (mal de Pott): A propósito de un caso. SITUA, 23(2), 46-52.

Radcliffe, C., & Grant, M. (2021). Pott Disease: A Tale of Two Cases. Pathogens, 10(9), 1158.

Saint Clair, J. P. G., Rabelo, Í. E. C., Rodriguez, J. E. R., de Castro, G. L., Printes, T. R. M., Sposina, L. B. C. F., ... & de Souza, G. M. (2022). Pott's disease associated with psoas abscess: Case report. Annals of Medicine and Surgery, 74, 103239.

Sorino, C., Agati, S., & Marchetti, S. N. G. (2021). Tuberculous Pleural Effusion and Pott Disease. Pleural Diseases, E-Book: Clinical Cases and Real-World Discussions, 133.

Suárez, E. U., Calpena, S., Álvarez, B., Górgolas, M., & Córdoba, R. (2021). A patient with Pott's disease. Revista Espanola de Quimioterapia: Publicacion Oficial de la Sociedad Espanola de Quimioterapia, 35(1), 97-99.

Van Hook, C. J., Taylor, A., Warner, B., Cool, C., Talusani, S., McManus, E. J., & Nanney, A. (2018). Successful Non-Surgical Treatment of Extensive Pott's Disease. In D47. TUBERCULOSIS: CASE REPORTS (pp. A6956-A6956). American Thoracic Society.

Published

22/09/2022

How to Cite

Fonseca, G. S. G. B. ., Borges, F. de A. ., Abreu, D. B. ., Marinho, R. P. ., Braga, R. de C. C. D. ., Barbosa, L. C. L. ., Rezende, E. W. T. de ., Araujo, L. de C. ., Santos , N. L. S. D. ., Chagas, A. L. P. ., Marques, M. L. da S. ., Freitas Júnior, L. F. de ., Salani, G. F. ., Mota, K. F. ., Pavão , A. H. L. J. ., Ferreira, L. R. T. ., Lima, L. S. ., Freitas, G. A. ., Vilanova, M. L. S. ., Almeida, D. K. M. ., Almeida, D. C. C. ., Mota, T. F. ., Lopes, A. T. Q. ., Portela, C. M. ., Vale, L. S. do, Rodrigues, G. M. C. ., & Queiroz , G. C. M. . (2022). Pott’s Disease associated with paraplegia: A case report of osteoarticular tuberculosis. E-Acadêmica, 3(3), e1533293. https://doi.org/10.52076/eacad-v3i3.293

Issue

Section

Health and Biological Sciences