Neurological manifestations in adults diagnosed with COVID-19
DOI:
https://doi.org/10.52076/eacad-v3i2.238Keywords:
COVID-19; SARS-CoV-2; Neurological manifestations; Neurologic manifestations; Neurological presentation; Hospitalized.Abstract
Objective: To analyze the occurrence of signs and symptoms of COVID-19 in patients hospitalized. Data sources: A systematic review was carried out. Information was collected from the PubMed BVSalud digital library databases, through descriptors (in English, Spanish, and Portuguese) such as SARS-CoV-2, COVID-19, neurological symptoms, hospitalization, and adults. The following filters were applied: articles published in the year 2021; descriptors presented only in the title or abstract; and Data synthesis: According to the articles studied, people were investigated for SARS-CoV-2 infection. There was a predominance of headache and myalgia (nonspecific symptoms). Through studies of recent conclusion, there is still a limited number of studies and information clarified about the clinical manifestations, including neurologic accomitment in patients diagnosed with COVID-19 hospitalized.
References
Amanat, M., Rezaei, N., Roozbeh, M. et al. (2021). Neurological manifestations as the predictors of severity and mortality in hospitalized individuals with COVID-19: a multicenter prospective clinical study. BMC Neurol 21, 116 (2021). https://doi.org/10.1186/s12883-021-02152-5
Baig, A.M, Khaleeq, A., Ali, U., & Syeda, H. (2020). “Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host virus interaction, and proposed neurotropic mechanisms,” ACS Chemical Neuroscience, 11(7), 995–998.
Chuang, D. et al. (2021). “Neurological manifestations as primary presentation of COVID-19 in hospitalized patients.” Acta neurologica Scandinavica vol. 143,5: 569-574. doi:10.1111/ane.13399
Deeb, A., Kumar P.C., Sakrani N., Trehan R.K., Papinenei V.R. (2021). Neurological Presentations of COVID-19: Characteristic Features in a Case Series of Hospitalized Patients from Abu Dhabi, UAE. Biomed Res Int.; 5822259.:10.1155/2021/5822259
Favas, T., Dev, P., Chaurasia R.N., et al. (2020). Neurologic manifestations of COVID-19: a systematic review and meta-analysis of proportions. Neurol Sci. 2020; 41:3437–3470. https://doi.org/10.1007/s10072-020-04801-y
Flores-Silva F.D. et al. (2020). Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2 Center for Biomedical Science, Feinstein Institute for Medical Research, Manhasset, NY, United States of America, 3 Stroke, Dementia & Heart Disease Laboratory, Western University, London, ON, Canada
Guadarrama P., Choreño J.A., Sanchez-Martınez C. M. et al. (2020). Neurologic Aspects of SARS-CoV-2 Infection: Mechanisms and Manifestations. Front Neurol. 2020 Sep 4; 11:1039. https://doi.org/10.3389/fneur.2020.01039
Helms, J., Kremer, H. et al. (2020). “Neurologic features in severe SARS-CoV-2 infection,” The New England Journal of Medicine, vol. 382, no. 23, pp. 2268–2270, 2020.
Herrmanstorfer, M., Ragusa M.A., Poggio, L. et al. (2020). Development of Simple and Sensitive Score to Assess the Risk of Pneumonia in COVID-19 Patients. Rev Invest Clin. 2020; 73 (5). https://doi.org/10.24875/RIC.20000295
Jiménez A., Garcıa M., Ruiz, J.L. et al. (2020). Neurologic manifestations of COVID-19. Gac Med Mex. 2020; 156:257. https://doi.org/10.24875/GMM.M20000380
Mao L., Jin H., Wang M. et al. (2020). “Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China,” JAMA Neurology, vol. 77, no. 6, pp. 683–690, 2020.
Mehta P., McAuley, D.F., Brown, M. et al.2020. “HLH across speciality collaboration, UK COVID-19: consider cytokine storm syndromes and immunosuppression,” Lancet, vol. 395, no. 10229, 1033- 1034, 2020.
Shah, V.A., Nalleballe, K., Zaghlouleh, M.E. et al. (2020). Acute encephalopathy is associated with worse outcomes in COVID-19 patients. Brain Behav Immun Health. 2020;8:100136. 10.1016/j.bbih.2020.100136
Shahjouei, S., Naderi S., Li, J. et al. (2020). Risk of stroke in hospitalized SARS-CoV-2 infected patients: a multinational study. EBioMedicine. 59:102939.
https://doi.org/10.1016/j.ebiom.2020.102939.
Sherry, H., Ettore, B., Raimund H., et al. (2020). Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium;
Tveito, K. (2020). “Cytokine storms in COVID-19 cases?” Tidsskrift for Den norske legeforening, vol. 23, p. 140, 2020.
Wang, D., Hu, B., Hu, C. et al. (2020). Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA. 2020; 323:1061. https:// doi.org/10.1001/jama.2020.1585 PMID: 32031570
World Health Organization. Coronavirus disease (COVID-19): situation report, 51. 2020. Available at: https://apps.who.int/iris/handle/10665/331475.
World Health Organization. Novel Coronavirus (2019-nCoV): situation report, 1. 2020. Available at: https://apps.who.int/iris/handle/10665/330760.
Wu, Y., Xu, X., Chen, Z. et al. (2020). “Nervous system involvement after infection with COVID-19 and other coronaviruses,” Brain, Behavior, and Immunity, vol. 87, pp. 18–22, 2020.
Xie, J., Wu, W., Li, S. et al. (2020). Clinical characteristics and outcomes of critically ill patients with novel coronavirus infectious disease (COVID-19) in China: a retrospective multicenter study. Intensive Care Med. 2020; 46:1863–1872. https://doi.org/10.1007/s00134-020-06211-2
Zhou, F., Yu, T., Du, R. et al. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395:1054–1062. https://doi.org/10.1016/S0140-6736(20)30566-3 PMID: 32171076
Zhu, N., Zhang, D., Wang, W. et al. (2020). A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020; 382:727–733. https://doi.org/10.1056/NEJMoa2001017
Zubair, A., McAlpine, L.S., Gardin, T. et al. (2020). “Neuropathogenesis and neurologic manifestations of the coronaviruses in the age of coronavirus disease 2019: a review,” JAMA Neurology, vol. 77, no. 8, 1018–1027.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 José Peixoto de Alencar Neto; Carla Pereira Santos Porto; Emilly Vasconcelos Borges Fontes; Halley Ferraro Oliveira; Márcio Maxi de Araújo Lima; Luiz Felipe Chaves Carvalho; Vivian Azevedo Marques de Campos
This work is licensed under a Creative Commons Attribution 4.0 International License.
Autores que publicam nesta revista concordam com os seguintes termos:
1) Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista.
2) Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
3) Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado.