Nutritional approach to Alzheimer´s disease: a literature review
DOI:
https://doi.org/10.52076/eacad-v3i2.134Keywords:
Alzheimer's disease; Neurodegenerative disease; Nutrients; Food.Abstract
Introduction: Alzheimer's disease (AD) is characterized as a neurodegenerative disease, and there is still no clinical cure for this disease, which progresses over time. However, many studies report and prove that through food, we can prevent and/or alleviate the symptoms of AD. Objective: To elucidate the nutrients and dietary patterns that can help in the prevention and treatment of Alzheimer's disease. Methodology: This study consisted of a narrative review of the literature and 30 scientific articles were selected for this review. Among the inclusion criteria, articles from the years 2014 to 2021, in the public domain, original research from scientific journals, monographs, thesis, dissertation and articles were selected. Exclusion criteria were articles not consistent with the topic, studies carried out on animals, research carried out with other neurodegenerative diseases and studies carried out with people under 30 years of age.
Results: Associated with the delay of cognitive decline, nutrients from omega 3, B vitamins, vitamins C, flavonoids and polyphenols showed positive results in relation to this disease. Conclusion: The inclusion of nutrients, physical activities and exercises for cognitive function are relevant to contribute to the reduction of the incidence of Alzheimer's Disease.
References
Abate, G., Marziano, M., Rungratanawanich, W., Memo, M., & Uberti, D. (2017, January 12). Nutrition and AGE-ing: Focusing on Alzheimer’s Disease. Oxidative Medicine and Cellular Longevity. https://www.hindawi.com/journals/omcl/2017/7039816/
Balbino, C. de S. (2021). A influência da alimentação no tratamento da doença de alzheimer / The influence of food in the treatment of alzheimer’s disease. Brazilian Journal of Health Review, 4(3), 10279–10293. https://doi.org/10.34119/bjhrv4n3-055
Barnard, N. D., Bush, A. I., Ceccarelli, A., Cooper, J., de Jager, C. A., Erickson, K. I., Fraser, G., Kesler, S., Levin, S. M., Lucey, B., Morris, M. C., & Squitti, R. (2014). Dietary and lifestyle guidelines for the prevention of Alzheimer’s disease. Neurobiology of Aging, 35, S74–S78. https://doi.org/10.1016/j.neurobiolaging.2014.03.033
Bhatti, G. K., Reddy, A. P., Reddy, P. H., & Bhatti, J. S. (2020). Lifestyle Modifications and Nutritional Interventions in Aging-Associated Cognitive Decline and Alzheimer’s Disease. Frontiers in Aging Neuroscience, 11. https://doi.org/10.3389/fnagi.2019.00369
De Cássia, B., Bigueti1, P., Zeitum De Lellis, J., Chioda, J., & Dias, R. (2018). Nutrientes essenciais na prevenção da doença de Alzheimer Essential nutrients in the prevention of Alzheimer’s disease. Revista Ciências Nutricionais Online, 2, 18–25. https://unifafibe.com.br/revistasonline/arquivos/cienciasnutricionaisonline/sumario/62/13042018180525.pdf
van den Brink, A. C., Brouwer-Brolsma, E. M., Berendsen, A. A. M., & van de Rest, O. (2019). The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer’s Disease—A Review. Advances in Nutrition, 10(6). https://doi.org/10.1093/advances/nmz054
Alves Carnauba, R. (2019). Rev Bras Nutr Func, 45(80). https://doi.org/10.32809/2176-4522.45.80.01
Clark, D. O., Xu, H., Moser, L., Adeoye, P., Lin, A. W., Tangney, C. C., Risacher, S. L., Saykin, A. J., Considine, R. V., & Unverzagt, F. W. (2019). MIND food and speed of processing training in older adults with low education, the MINDSpeed Alzheimer’s disease prevention pilot trial. Contemporary Clinical Trials, 84, 105814. https://doi.org/10.1016/j.cct.2019.105814
Programa Nacional para Promoção de Alimentação Saudável. (n.d.). Retrieved May 12, 2022, from https://alimentacaosaudavel.dgs.pt/activeapp2020/wp-content/uploads/2019/12/Relato%CC%81rio_PNPAS_2019.pdf
De Seiça, M., Dias, R., Costa, D., & De Revisão, A. (n.d.). Mestrado Integrado em Medicina -Trabalho final : O impacto nutricional na doença de Alzheimer área científica de Nutrição. Trabalho realizado sob a orientação de: PROFESSORA DOUTORA LÈLITA SANTOS. Retrieved May 12, 2022, from https://estudogeral.sib.uc.pt/bitstream/10316/90048/1/Tese%20Final%20Mariana%20Costa.pdf
Cremonini, A. L., Caffa, I., Cea, M., Nencioni, A., Odetti, P., & Monacelli, F. (2019). Nutrients in the Prevention of Alzheimer’s Disease. Oxidative Medicine and Cellular Longevity, 2019, 1–20. https://doi.org/10.1155/2019/9874159
Féart, C. (2009). Adherence to a Mediterranean Diet, Cognitive Decline, and Risk of Dementia. JAMA, 302(6), 638. https://doi.org/10.1001/jama.2009.1146
Dietas associadas à incidência reduzida da doença de Alzheimer Diets associated with the reduced incidence of alzheimer’s. (n.d.). Retrieved May 12, 2022, from https://repositorio.pucgoias.edu.br/jspui/bitstream/123456789/766/1/TCC%20Joabeth%20Rezende%20Ferreira.pdf
Hu, N., Yu, J.-T., Tan, L., Wang, Y.-L., Sun, L., & Tan, L. (2013). Nutrition and the Risk of Alzheimer’s Disease. BioMed Research International, 2013, 1–12. https://doi.org/10.1155/2013/524820
Kryscio, R. J., Abner, E. L., Caban-Holt, A., Lovell, M., Goodman, P., Darke, A. K., Yee, M., Crowley, J., & Schmitt, F. A. (2017). Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer’s Disease by Vitamin E and Selenium Trial (PREADViSE). JAMA Neurology, 74(5), 567. https://doi.org/10.1001/jamaneurol.2016.5778
Leal, T. (n.d.). UniAGES Centro Universitário Bacharelado em Nutrição Manejo Nutricional No Alzheimer: uma revisão integrativa Paripiranga 2021. Retrieved May 12, 2022, from https://repositorio.animaeducacao.com.br/bitstream/ANIMA/14369/1/Monografia%20Tawany-%20Corrigida%20e%20formatada.pdf
Machado, J., Caram, C. L. B., Frank, A. A., Soares, E. de A., & Laks, J. (2009). [Nutritional status in Alzheimer’s disease]. Revista Da Associacao Medica Brasileira (1992), 55(2), 188–191. https://doi.org/10.1590/s0104-42302009000200024
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Bennett, D. A., & Aggarwal, N. T. (2015). MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association, 11(9), 1007–1014. https://doi.org/10.1016/j.jalz.2014.11.009
Nooyens, A. C. J., Yildiz, B., Hendriks, L. G., Bas, S., van Boxtel, M. P. J., Picavet, H. S. J., Boer, J. M. A., & Verschuren, W. M. M. (2021). Adherence to dietary guidelines and cognitive decline from middle age: the Doetinchem Cohort Study. The American Journal of Clinical Nutrition, 114(3), 871–881. https://doi.org/10.1093/ajcn/nqab109.
Phillips, M. C. L., Deprez, L. M., Mortimer, G. M. N., Murtagh, D. K. J., McCoy, S., Mylchreest, R., Gilbertson, L. J., Clark, K. M., Simpson, P. V., McManus, E. J., Oh, J.-E., Yadavaraj, S., King, V. M., Pillai, A., Romero-Ferrando, B., Brinkhuis, M., Copeland, B. M., Samad, S., Liao, S., & Schepel, J. A. C. (2021). Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease. Alzheimer’s Research & Therapy, 13(1). https://doi.org/10.1186/s13195-021-00783-x.
Carvalho, A., Pinto, M., Renata, D., Oliveira, S., Coorientado, B., & Sampaio, D. (n.d.). Envelhecimento saudável: o papel da alimentação e nutrição Healthy aging: the role of diet and nutrition. Retrieved May 12, 2022, from https://repositorio-aberto.up.pt/bitstream/10216/133106/2/449401.pdf
Priulli, E., Pires, C. R. F., & Cezar, T. C. M. (2020). Alimentação como fator de proteção da doença de Alzheimer. Research, Society and Development, 9(10), e4259108895–e4259108895. https://doi.org/10.33448/rsd-v9i10.8895
De, L., & Ribeiro, S. (2017). Universidade Federal de Goiás Faculdade de Nutrição Alimentação Saudável e Cognição: um estudo da interface em idosos autônomos de Goiânia. https://repositorio.bc.ufg.br/bitstream/ri/12466/5/TCCG%20-%20Nutri%C3%A7%C3%A3o%20-%20Lorena%20de%20Sousa%20Ribeiro%20-%202017.pdf
Richard, E., Laughlin, G., Kritz-Silverstein, D., Reas, E., Barrett-Connor, E., & McEvoy, L. (2018). Dietary Patterns and Cognitive Function among Older Community-Dwelling Adults. Nutrients, 10(8), 1088. https://doi.org/10.3390/nu10081088
Román, G. C., Jackson, R. E., Gadhia, R., Román, A. N., & Reis, J. (2019). Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease. Revue Neurologique, 175(10), 724–741. https://doi.org/10.1016/j.neurol.2019.08.005
Rusek, M., Pluta, R., Ułamek-Kozioł, M., & Czuczwar, S. J. (2019). Ketogenic Diet in Alzheimer’s Disease. International Journal of Molecular Sciences, 20(16), 3892. https://doi.org/10.3390/ijms20163892
Faculdades ESEFAP -Tupã -São Paulo. (2011). http://www.cesumar.br/prppge/pesquisa/epcc2011/anais/edson_pilger_dias.pdf
Shishtar, E., Rogers, G. T., Blumberg, J. B., Au, R., & Jacques, P. F. (2020). Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort. The American Journal of Clinical Nutrition, 112(2), 343–353. https://doi.org/10.1093/ajcn/nqaa079
Da, E., Professora, S., Me, O., Maína, R., Pereira, C., & Brasília. (2018). EnsaioE CENTRO UNIVERSITÁRIO DE BRASÍLIA -UniCEUB FACULDADE DE CIÊNCIAS DA EDUCAÇÃO E SAÚDE CURSO DE NUTRIÇÃO ALIMENTAÇÃO COMO FATOR DE PROTEÇÃO PARA PACIENTES COM ALZHEIMER. https://repositorio.uniceub.br/jspui/bitstream/235/12643/1/21503459.pdf
Swaminathan, A., & Jicha, G. A. (2014). Nutrition and prevention of Alzheimerâ€TMs dementia. Frontiers in Aging Neuroscience, 6. https://doi.org/10.3389/fnagi.2014.00282
Tanaka, T., Talegawkar, S., Jin, Y., Colpo, M., Ferrucci, L., & Bandinelli, S. (2018). Adherence to a Mediterranean Diet Protects from Cognitive Decline in the Invecchiare in Chianti Study of Aging. Nutrients, 10(12), 2007. https://doi.org/10.3390/nu10122007
Taylor, M. K., Swerdlow, R. H., & Sullivan, D. K. (2019). Dietary Neuroketotherapeutics for Alzheimer’s Disease: An Evidence Update and the Potential Role for Diet Quality. Nutrients, 11(8), 1910. https://doi.org/10.3390/nu11081910
Thota, R. N., Rosato, J. I., Dias, C. B., Burrows, T. L., Martins, R. N., & Garg, M. L. (2020). Dietary Supplementation with Curcumin Reduce Circulating Levels of Glycogen Synthase Kinase-3β and Islet Amyloid Polypeptide in Adults with High Risk of Type 2 Diabetes and Alzheimer’s Disease. Nutrients, 12(4). https://doi.org/10.3390/nu12041032
Steffenon Weber, I. T., Conte, F. A., Busnello, M. B., & Bento Franz, L. B. (2019). NUTRIÇÃO E DOENÇA DE ALZHEIMER NO IDOSO: UMA REVISÃO. Estudos Interdisciplinares Sobre O Envelhecimento, 24(3). https://doi.org/10.22456/2316-2171.85168
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Luísa Simões Almeida ; Amanda Pupe Zupi
This work is licensed under a Creative Commons Attribution 4.0 International License.
Autores que publicam nesta revista concordam com os seguintes termos:
1) Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista.
2) Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
3) Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado.