Autoimmune Presentation Rhupus Like of lung cancer non-small cells

Abstract

Introduction: Rhupus, or Rhupus Syndrome, is a rare rheumatologic disease characterized by the overlapping of Systemic Lupus Erythematosus and Rheumatoid Arthritis in patients meeting SLICC and ACR/EULAR criteria. Objective: To describe the clinical case of a patient with non-small cell lung cancer presenting with Rhupus Syndrome and to review the literature on Rhupus and its clinical features. Methodology: Case report type of study descriptive qualitative with information obtained directly from the medical records kept during hospitalization. Discussion: Rhupus Syndrome, characterized by the overlapping of SLE and RA, has two most common presentations, the first are patients who begin with RA, and then are diagnosed with SLE, comprising 2/3 of the cases of Rhupus. The second presentation consists of patients initially with SLE or with both diseases diagnosed at the beginning. As this is a rare syndrome, there are no validated diagnostic criteria for this disease. Conclusion: Although the interposition of rheumatologic diseases is not rare, Rhupus has an estimated prevalence of 0.09% of the population. Diagnosis may be difficult because there are no well-defined diagnostic criteria and because of its rarity; however, this diagnosis may be determinant for an adequate approach to the patient and a better prognosis, reducing complications related to SLE and/or RA.